A total of 42 cases of Hodgkin's disease was obtained from the file of Department of
Pathology, College of Medicine, Seoul National University during a period of 7 years
from 1976 to 1982. These cases were critically reviewed microscopically and classified
according to Rye modification of Lukes-Butler classification.
In 42 cases of Hodgkin's disease the patients ranged in age from 5 to 75 years, with
an average of 35.1 years. Male to female ratio was 5 : 1. Histological types consisted of
17(40.5%) mixed cellularity, 12 (28.6%) lymphocyte depletion, 7(16.6%) lymphocyte
predominance and 6(14.3%) nodular sclerosis. Biopsy sites were lymph nodes in 36
cases, spleen in 2 and gastrointestinal tract in 4. Comparing with previously reported
material of non-Hodgkin's lymphoma in our department, there were 25 cases of
Hodgkin's disease and 160 cases of non-Hodgkin's lymphoma during 1976-1980, thus
the Hodgkin's disease comprised 13.5% of all malignant lymphoma.
In conclusion, Hodgkin's disease in Korea seems to be characterized by relatively low
incidence comparing with non-Hodgkin's lymphoma, and low relative frequency of
nodular sclerosis type, while lymphocyte depletion type is relatively high.
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